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| JAM-A/CD321/F11R Rabbit mAb |
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| LTA24711 |
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| 100ul |
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$750
In stock
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| Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. |
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| JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1 |
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| 50848,sc-17427,sc-25629,F11R,CD321,JAM,JAM1,JAMA,JCAM,KAT,PAM-1,F11 receptor,junctional adhesion molecule A,junctional adhesion molecule 1,platelet F11 receptor,platelet adhesion molecule 1,Q9Y624,F11r,F11 Receptor,Junctional Adhesion Molecule 1,Platelet Adhesion Molecule 1,Platelet F11 Receptor,Junctional Adhesion Molecule A,CD321 Antigen,JAM-1,JAM-A |
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| Human |
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| 50848 |
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| Q9Y624 |
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| SVTVHSSEPEVRIPENNPVKLSCAYSGFSSPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVGVIVAA |
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| Recombinant fusion protein containing a sequence corresponding to amino acids 28-242 of human JAM-A/CD321/F11R (NP_058642.1). |
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| Rabbit |
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| Affinity Purified Monoclonal IgG |
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| WB, ELISA |
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| Human |
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| 33kDa |
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| WB,1:5000 - 1:10000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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| .jpg )
Western blot analysis of lysates from A-431 cells using JAM-A/CD321/F11R Rabbit mAb (LTA24711) at 1:10000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 180s. |
