[KD Validated] PSAP Rabbit mAb

Product Name
[KD Validated] PSAP Rabbit mAb
Catalog Number
LTA24738
Quantity
100ul
Price
$750 In stock
Description
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Alias
GLBA; SAP1; SAP2; PSAPD; PARK24
Keywords
5660,sc-27014,sc-27018,sc-27012,sc-32875,A1 activator,Cerebroside sulfate activator,Co beta glucosidase,Component C,CSAct,Dispersin,GLBA,Glucosylceramidase activator,Proactivator polypeptide,prosaposin,Protein C,PSAP,SAP 1,SAP 2 Saposin D,SAP1,proactivator polypeptide,sphingolipid activator protein-1,P07602,Prosaposin,Sphingolipid Activator Protein-1,Proactivator Polypeptide,Variant Gaucher Disease And Variant Metachromatic Leukodystrophy
Gene Template Species
Human
Gene/Protein ID
5660
SWISS ID
P07602
Antigen Sequence
KEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 275-524 of human PSAP (NP_002769.1).
Animal Source
Rabbit
Antibody Type
Affinity Purified Monoclonal IgG
Applications
WB, ELISA
Cross-Reactivity
Human
Molecular Weight
58kDa
Recommended Dilution
WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements.
Stability and Storage

Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.

Image
 [KD Validated] PSAP Rabbit mAb

Western blot analysis of lysates from wild type (WT) and PSAP knockdown (KD) 293T cells using [KD Validated] PSAP Rabbit mAb (LTA24738) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 90s.

  • 4 Units in Stock

Ask a Question

$750.00

Add to Cart:
LifeTein LifeTein provides custom peptide synthesis service, recombinant proteins, peptides, cytokines, custom antibody service and custom protein service. LifeTein is the world leader in fast peptide synthesis service with lab facility located in New Jersey USA. LifeTein Logo 100 Randolph Road, Suite 2D, Somerset USA New Jersey 08873
Copyright © 2025 LifeTein.com. Powered by LifeTein