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Dirucotide, MBP8298, DENPVVHFFKNIVTPRT |
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DENPVVHFFKNIVTPRT, Asp - Glu - Asn - Pro - Val - Val - His - Phe - Phe - Lys - Asn - Ile - Val - Thr - Pro - Arg - Thr |
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5 mg |
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>95% |
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LT2668 |
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N/A |
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2013.37 |
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C92H141N25O26 |
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MBP8298 is a synthetic peptide with a sequence corresponding to amino acid residues 82–98 of human myelin basic protein (DENPVVHFFKNIVTPRT). Dirucotide is a synthetically peptide of 17 amino acids. The peptide is a section of myelin basic protein (MBP) in humans. Dirucotide was used for the treatment of multiple sclerosis (MS). MBP8298 was evaluated in a placebo-controlled double-blinded Phase II clinical trial in patients with progressive MS. |