| Mouse BACE-1 Protein (LTP10158) |
| LTP10158 |
| 100ug |
|
$360 In stock |
| The beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) initiates the generation of amyloid-? (A?), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD). Clinical failures of anti-A? therapies in dementia stages suggest that treatment has to start in the early, asymptomatic disease states. |
| Recombinant Mouse BACE-1 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Thr22-Thr457. |
| BACE-1 |
| Mouse |
| P56818 |
| Thr22-Thr457 |
| The protein has a predicted MW of 49.49 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result. |
| 0 |
| C-His |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| ![Mouse BACE-1 Protein (LTP10158)](/peptide-product/images/protein-products/LTP10158/20220214105018.png) |