| Mouse GARP&Latent TGF beta 1 Complex Protein (LTP10494) |
| LTP10494 |
| 100ug |
|
$473 In stock |
| GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-? and thus promoting secretion and activation of TGF-?. Integrin ?v?8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-? from the TGF-?&GARP complex. |
| Recombinant Mouse GARP&Latent TGF beta 1 Complex Protein is expressed from Expi293 with His tag at the N-terminal. It contains Ala18-Leu628(GARP)&Leu30-Ser390(Latent TGF beta 1). |
| GARP&Latent TGF beta 1 Complex |
| Mouse |
| G3XA59(GARP)&P04202(Latent TGF beta 1) |
| Ala18-Leu628(GARP) & Leu30-Ser390(Latent TGF beta 1) |
| The protein has a predicted MW of 66.6 kDa (GARP)&41.3 kDa (Latent TGF beta 1). Due to glycosylation, the protein migrates to 70-80 kDa (GARP)&13 kDa&42-50 kDa (Latent TGF beta 1) based on the Tris-Bis PAGE result. |
| 0 |
| N-His |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| ![Mouse GARP&Latent TGF beta 1 Complex Protein (LTP10494)](/peptide-product/images/protein-products/LTP10494/20211229091904.png) |