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| Mouse IgG1 Fc Protein (LTP10963) |
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| LTP10963 |
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| 100ug |
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$136 In stock |
| Recombinant murine Fc fragment contains the hinge region, CH2, and CH3 region of the mouse IgG1 isotype. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (Fc?R) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. |
| Recombinant Mouse IgG1 Fc Protein is expressed from Expi293 without tag. It contains Val98-Lys324. |
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| IgG1 Fc |
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| Mouse |
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| P01868 |
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| Val98-Lys324 |
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| The protein has a predicted MW of 25.7 kDa. Due to glycosylation, the protein migrates to 34-36 kDa based on the Tris-Bis PAGE result. |
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| The affinity constant of 15.09 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| No Tag |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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