Mouse IL-17R alpha/CD217 Protein (LTP10237)

Product Name
Mouse IL-17R alpha/CD217 Protein (LTP10237)
Catalog Number
LTP10237
Quantity
100ug
Price
$339 In stock
Background
Interleukin 17 (also known as CTLA?8) is a T cell?expressed pleotropic cytokine. IL?17 binds to IL?17 receptor (IL?17 R) which shares no homology with any known family of receptors. While the expression of IL?17 is restricted to activated T cells, the IL?17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL?17 R gene was localized to chromosome 22.
Description
Recombinant Mouse IL-17R alpha/CD217 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Ser32-Trp322.
Target
IL-17R alpha/CD217
Species
Mouse
Gene/Protein ID
Q60943
Exact Sequence
Ser32-Trp322
Molecular Weight
The protein has a predicted MW of 60.1 kDa. Due to glycosylation, the protein migrates to 95-110 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 9.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Tag
C-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Mouse IL-17R alpha/CD217 Protein (LTP10237)
  • 5 Units in Stock

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