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| NF2/Merlin Rabbit mAb |
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| LTA24747 |
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| 100ul |
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$750
In stock
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| This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of this protein's function has been implicated in tumorigenesis and metastasis. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. |
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| ACN; SCH; BANF; merlin-1 |
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| 4771,sc-331,sc-332,sc-28247,NF2,ACN,BANF,SCH,neurofibromin 2,merlin,moesin-ezrin-radixin like,moesin-ezrin-radixin-like protein,moesin-ezrin-radizin-like protein,neurofibromin 2 (bilateral acoustic neuroma),schwannomerlin,schwannomin,P35240,Neurofibromin 2,Schwannomin,Neurofibromin 2 (Bilateral Acoustic Neuroma),Moesin-Ezrin-Radixin-Like Protein,Moesin-Ezrin-Radixin Like,Schwannomerlin,Moesin-Ezrin-Radizin-Like Protein,Neurofibromin 2 (Merlin),Neurofibromin-2,Merlin |
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| Human |
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| 4771 |
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| P35240 |
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| EEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKLTLQSAKSRVAFFEEL |
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| Recombinant fusion protein containing a sequence corresponding to amino acids 347-595 of human NF2/Merlin (NP_000259.1). |
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| Rabbit |
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| Affinity Purified Monoclonal IgG |
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| WB, ELISA |
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| Human, Mouse, Rat |
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| 70kDa |
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| WB,1:3000 - 1:12000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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| .jpg )
Western blot analysis of various lysates using NF2/Merlin Rabbit mAb (LTA24747) at 1:3000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 30s. |
