Occludin Rabbit mAb

Product Name
Occludin Rabbit mAb
Catalog Number
LTA24780
Quantity
100ul
Price
$750 In stock
Description
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
Alias
BLCPMG; PTORCH1; PPP1R115
Keywords
100506658,sc-8145,sc-8144,sc-27151,sc-5562,OCLN,BLCPMG,PPP1R115,occludin,phosphatase 1,regulatory subunit 115,tight junction protein occludin,Q16625,Ocln,Occludin,Phosphatase 1,Regulatory Subunit 115,Tight Junction Protein Occludin TM4 Minus,Tight Junction Protein Occludin,PTORCH1
Gene Template Species
Human
Gene/Protein ID
100506658
SWISS ID
Q16625
Antigen Sequence
GGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 405-522 of human Occludin (NP_001192183.1).
Animal Source
Rabbit
Antibody Type
Affinity Purified Monoclonal IgG
Applications
WB, ELISA
Cross-Reactivity
Mouse, Rat
Molecular Weight
59kDa
Recommended Dilution
WB,1:2000 - 1:8000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements.
Stability and Storage

Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.

Image
 Occludin Rabbit mAb

Western blot analysis of lysates from Mouse liver using Occludin Rabbit mAb (LTA24780) at 1:2000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 30s.

  • 4 Units in Stock

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$750.00

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