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| P-cadherin Rabbit mAb |
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| LTA24812 |
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| 100ul |
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$750
In stock
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| This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). |
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| CDHP; HJMD; PCAD |
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| 1001,sc-31027,sc-31026,sc-1501,sc-7893,sc-10733,Cadherin 3,CDH3,CDHP,HJMD,P cadherin,PCAD,P-cadherin,Placental cadherin,cadherin 3,cadherin-3,type 1,P-cadherin (placental),calcium-dependent adhesion protein,placental,P22223,Type 1,P-Cadherin (Placental),P-Cadherin,Calcium-Dependent Adhesion Protein,Placental,Placental Cadherin,Cadherin-3 |
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| Human |
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| 1001 |
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| P22223 |
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| DWVVAPISVP ENGKGPFPQR LNQLKSNKDR DTKIFYSITG PGADSPPEGV FAVEKETGWL LLNKPLDREE IAKYELFGHA VSENGASVED PMNISIIVTD QNDHKPKFTQ DTFRGSVLEG VLPGTSVMQV TATDEDDAIY TYNGVVAYSI HSQEPKDPHD LMFTIHRSTG TISVISSGLD REKVPEYTLT IQATDMDGDG STTTAVAVVE ILDANDNAPM FDPQKYEAHV PENAVGHEVQ RLTVTDLDAP NSPAWRATYL IMGGDDGDHF TITTHPESNQ GILTTRKGLD FEAKNQHTLY VEVTNEAPFV LKLPTSTATI VVHVEDVNEA PVFVPPSKVV EVQEGIPTGE PVCVYTAEDP DKENQKISYR ILRDPAGWLA MDPDSGQVTA VGTLDREDEQ FVRNNIYEVM VLAMDNGSPP TTGTGTLLLT LIDVNDHGPV PEPRQITICN QSPVRQVLNI TDKDLSPHTS PFQAQLTDDS DIYWTAEVNE EGDTVVLSLK KFLKQDTYDV HLSLSDHGNK EQLTVIRATV CDCHGHVETC PGPWKGG |
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| Recombinant fusion protein containing a sequence corresponding to amino acids 108-654 of human P-cadherin (NP_001784.2). |
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| Rabbit |
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| Affinity Purified Monoclonal IgG |
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| WB, ELISA |
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| Human |
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| 91kDa |
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| WB,1:1500 - 1:6000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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| .jpg )
Western blot analysis of various lysates using P-cadherin Rabbit mAb (LTA24812) at 1:3000 dilution incubated at room temperature for 1.5 hours.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Negative control (NC): SH-SY5Y|Exposure time: 45s. |
