|
| SARS-COV-2 Spike S1 Protein (LTP10949) |
|
| LTP10949 |
|
| 100ug |
|
|
$450 In stock |
| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
| Recombinant SARS-COV-2 Spike S1 Protein is expressed from Expi293 with hFc tag and Avi tag at the C-terminal. It contains Gln14-Arg683. |
|
| Spike S1 |
|
| SARS-COV-2 |
|
| QHD43416.1 |
|
| Gln14-Arg683 |
|
| The protein has a predicted MW of 102.6 kDa. Due to glycosylation, the protein migrates to 130-140 kDa based on the Tris-Bis PAGE result. |
|
| The affinity constant of 3.80 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
|
| C-hFc-Avi |
|
| Expi293 |
|
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
|
| Less than 1EU per ug by the LAL method. |
|
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
|
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
| Shipped at ambient temperature. |
|
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
|
|  |
