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| SOCS1 Rabbit mAb |
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| LTA24706 |
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| 100ul |
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$750
In stock
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| This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. |
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| JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; TIP-3; AISIMD; SOCS-1 |
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| 8651,sc-7006,sc-9021,SOCS1,CIS1,CISH1,JAB,SOCS-1,SSI-1,SSI1,TIP3,suppressor of cytokine signaling 1,JAK binding protein,STAT induced SH3 protein 1,STAT-induced STAT inhibitor 1,TIP-3,Tec-interacting protein 3,cytokine-inducible SH2 protein 1,O15524,Suppressor Of Cytokine Signaling 1,STAT-Induced STAT Inhibitor 1,Tec-Interacting Protein 3,Cytokine-Inducible SH2 Protein 1,STAT Induced SH3 Protein 1,JAK Binding Protein,JAK-Binding Protein |
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| Human |
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| 8651 |
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| O15524 |
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| MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGT |
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| A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOCS1 (NP_003736.1). |
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| Rabbit |
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| Affinity Purified Monoclonal IgG |
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| IHC-P, ELISA |
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| Human, Mouse, Rat |
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| 24kDa |
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| IHC-P,1:100 - 1:1000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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| .jpg )
Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma tissue using SOCS1 Rabbit mAb (LTA24706) at a dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining. |
