TSLP Rabbit mAb

Product Name
TSLP Rabbit mAb
Catalog Number
LTA24827
Quantity
100ul
Price
$750 In stock
Description
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants.
Alias
TSLP
Keywords
85480,TSLP,thymic stromal lymphopoietin,Q969D9,Tslp,Thymic Stromal Lymphopoietin
Gene Template Species
Human
Gene/Protein ID
85480
SWISS ID
Q969D9
Antigen Sequence
YDFTNCDFEK IKAAYLSTIS KDLITYMSGT KSTEFNNTVS CSNRPHCLTE IQSLTFNPTA GCASLAKEMF AMKTKAALAI WCPGYSETQI NATQAMKKRR KRKVTTNKCL EQVSQLQGLW RRFNRPLLKQ Q
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 29-159 of human TSLP(NP_149024.1).
Animal Source
Rabbit
Antibody Type
Affinity Purified Monoclonal IgG
Applications
WB, ELISA
Cross-Reactivity
Human
Molecular Weight
18kDa
Recommended Dilution
WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Stability and Storage

Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.

Image
 TSLP Rabbit mAb

Western blot analysis of lysates from Active Recombinant Human TSLP Protein (RP01172) using TSLP Rabbit mAb (LTA24827) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 5ng per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 60s.

  • 4 Units in Stock

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$750.00

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