Monitoring T cell–dendritic cell interactions in vivo using labeled peptides

The SrtA substrates Biotin–aminohexanoic acid–LPETGS and SELPETGG were used to interact with immune cells ‘Labelling Immune Partnerships by SorTagging Intercellular Contacts’ (LIPSTIC). The peptide-receptor interactions enable the direct measurement of dynamic cell-cell interactions. The peptides are flexible tools with different receptor-ligand pairs and a range of detectable labels.

 

Nature, Monitoring T cell–dendritic cell interactions in vivo by intercellular enzymatic labeling

Peptide Biotin–aminohexanoic acid–LPETGS, SELPETGG was purchased from LifeTein.