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| Biotinylated Human B7-H6 Protein (LTP10201) |
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| LTP10201 |
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| 100ug |
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$789 In stock |
| B7-H6 is a glycosylated member of the B7 family of immune co?stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues. |
| Recombinant Biotinylated Human B7-H6 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Asp25-Ser262. |
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| B7-H6 |
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| Human |
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| Q68D85 |
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| Asp25-Ser262 |
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| The protein has a predicted MW of 29.6 kDa. Due to glycosylation, the protein migrates to 48-65 kDa based on the Tris-Bis PAGE result. |
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| The affinity constant of 0.227 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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