Human Calprotectin (S100A8&S100A9) Protein (LTP10969)

Product Name
Human Calprotectin (S100A8&S100A9) Protein (LTP10969)
Catalog Number
LTP10969
Quantity
100ug
Price
$450 In stock
Background
Calprotectin, a member of the widespread calcium-binding S-100 protein family, is present in remarkably high concentration in the cytoplasm of human neutrophils. The calprotectin molecule is composed of light (MRP8) and heavy (MRP14) subunits. Although not secreted from intact neutrophils, calprotectin release from dead and dying neutrophils creates high concentrations of the protein in inflammatory or abscess fluids and in the intestinal tract lumen of patients with inflammatory bowel disease.
Description
Recombinant Human Calprotectin (S100A8&S100A9) Protein is expressed from E.coli with His tag at the C-terminal. It contains Met1-Glu93(S100A8)&Thr2-Pro114(S100A9).
Target
Calprotectin (S100A8&S100A9)
Species
Human
Gene/Protein ID
P05109(S100A8)&P06702(S100A9)
Exact Sequence
Met1-Glu93(S100A8) & Thr2-Pro114(S100A9)
Molecular Weight
The protein has a predicted MW of 11.7 kDa(S100A8)&13.2 kDa(S100A9) same as Tris-Bis PAGE result.
Activity
0
Tag
C-His
Express System
E.coli
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in 2mM DTT, PBS (pH 7.2). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human Calprotectin (S100A8&S100A9) Protein (LTP10969)
  • 5 Units in Stock

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