Product Description | Leptin (Greek leptos meaning thin) plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It may function as part of a signaling pathway that acts to regulate the size of the body fat depot. Leptin (116-130) was shown to mimic the effects of the native leptin in terms of body weight gain and food intake, and to elicit LH and prolactin (PRL) secretion in vivo. |
Scientific Background | Leptin (116-130), mouse is a 15-residue synthetic peptide with the sequence Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser. The sequence contains 1 cysteine residue, providing potential thiol/disulfide chemistry when the thiol is available. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
