Leptin (116-130), mouse

Leptin (Greek leptos meaning thin) plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It may function as part of a signaling pathway that acts to regulate the size of the body fat depot. Leptin (116-130) was shown to mimic the effects of the native leptin in terms of body weight gain and food intake, and to elicit LH and prolactin (PRL) secretion in vivo.